Condition

Pseudoexfoliation Glaucoma

Also known as Exfoliation Glaucoma, Pseudoexfoliative Glaucoma, PXF Glaucoma, PEX Glaucoma

Updated May 16, 2026For educational purposes only. Not a substitute for medical advice. See our terms.

Bottom Line

Pseudoexfoliation glaucoma happens when flaky material builds up in the eye and blocks fluid outflow. It often causes higher, more jumpy eye pressure than common open-angle glaucoma.

Pseudoexfoliation syndrome makes a flaky, dandruff-like material inside the eye. The material can collect in the eye's drain, where fluid leaves the front of the eye 1.

When this buildup raises eye pressure and damages the optic nerve, it is called pseudoexfoliation glaucoma. It is a common cause of secondary open-angle glaucoma in older adults 2.

Pressure can rise quickly and vary a lot. Treatment may include drops, laser, cataract surgery planning, or glaucoma surgery 1.

Why This Type Needs Close Follow-Up

Pseudoexfoliation glaucoma can be harder to control than common open-angle glaucoma. Eye pressure may be higher, and pressure spikes can happen between visits 1.

Pseudoexfoliation can also weaken the tiny supports that hold the natural lens. Tell your cataract surgeon if any doctor has seen pseudoexfoliation material 3.

  • Drops. These lower pressure and may need adjustment over time.
  • Laser. Selective laser trabeculoplasty can work well in many eyes.
  • Surgery. Surgery may be needed if pressure remains too high.

Common Questions About Pseudoexfoliation Glaucoma

No. Pseudoexfoliation means flaky material is present inside the eye. Glaucoma means the optic nerve is being damaged.

Next Steps

  1. 1Book a glaucoma exam if pseudoexfoliation material was seen in either eye.
  2. 2Ask whether your pressure should be checked at different times of day.
  3. 3Tell any cataract surgeon that you have pseudoexfoliation.
  4. 4Use pressure drops exactly as directed and report side effects quickly.
  5. 5Go to the emergency room for sudden eye pain, halos with nausea, or sudden vision loss.

Find specialists for Pseudoexfoliation Glaucoma

Board-certified ophthalmologists who treat Pseudoexfoliation Glaucoma.

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