Dr. Matthew Santos

Dr. Matthew C. Santos is a cornea and anterior segment specialist at Penn Medicine’s Scheie Eye Institute. He earned his medical degree from Brown University, completed ophthalmology residency at Washington University in St. Louis, and pursued fellowship training at Wills Eye Hospital. Dr. Santos treats the full range of corneal disorders, from infections and dystrophies to keratoconus and post-surgical complications. He offers advanced endothelial keratoplasty techniques, collagen cross-linking for progressive ectasia, and thoughtful approaches to complex cataract surgery and secondary intraocular lens issues. Patients appreciate his steady communication style, attention to comfort, and emphasis on shared decision-making. In collaboration with optometry and contact lens teams, he focuses on restoring clear vision and long-term ocular surface health. Dr. Santos is board certified by the American Board of Ophthalmology and sees adult patients at Scheie Eye Institute locations in Philadelphia and Media.