Dr. Miller is interested in macular degeneration, diabetic retinopathy, retinal detachment, retinal vascular occlusions, trauma, macular telangiectasia, and complex medical and surgical retinal problems. He uses the latest examination and diagnostic imaging techniques in hopes of providing earlier diagnosis and treatment. Surgically, he specializes in retinal detachment repair, including complex retinal detachments related to proliferative vitreoretinopathy or traumatic injuries, macular holes, epiretinal membranes (macular pucker), and dislocated lenses. Dr. Miller is highly regarded by patients and staff for his friendly demeanor, ease of communication, and clinical competency.

Dr. Miller maintains an active research program in addition to his strong clinical retina practice. As a clinician scientist, his work focuses both on clinical research and the basic mechanisms of retinal disease through study in the laboratory. In the Ines and Frederick Yeatts Retina Research Laboratory at Mass Eye and Ear, he has explored the mechanisms of retinal toxicity of systemic medications. Ongoing work explores the pathogenesis of age-related macular degeneration, macular telangiectasia, macular hole, and drug retinal toxicities.

Additionally, he plays an important role training ophthalmology residents and retina fellows in the clinic and operating room as a Core Faculty Member of the Harvard Ophthalmology Residency program and the Associate Director of the Vitreoretinal Fellowship.