Dr. Luciano Greig

Luciano C. Greig, MD, PhD is an Assistant Professor in the UCSF Department of Ophthalmology, where he leads the Greig Lab. His research focuses on retinal development and regeneration, with the goal of developing stem cell therapies for currently irreversible causes of vision loss.

The Greig Lab investigates the genetic regulation of cell identity acquisition in the retina. By understanding how gene regulatory networks direct the formation of diverse retinal neuron types, Dr. Greig aims to formulate therapeutic strategies to repair retinal pathology. This work has the potential to lead to new treatments for conditions such as diabetic retinopathy, macular degeneration, and myopia.

A key area of interest is the reprogramming of Müller glia into replacement retinal ganglion cells or photoreceptors. Additionally, the lab develops new genetic analysis and manipulation methods in mice to track cells during identity reprogramming experiments. Through this research, Dr. Greig and his team hope to contribute to future therapies that restore vision for patients with retinal diseases.